Understanding Peyronie’s Disease and the Treatments Available

Meet Dr. Charles Osterberg

Dr. E. Charles Osterberg is a board-certified urologist at Urology Austin with advanced fellowship training in male genitourinary reconstruction. He is one of the few specialists in Texas dedicated to treating Peyronie’s disease and other complex urologic conditions that impact quality of life. Known for his compassionate, patient-centered care, Dr. Osterberg uses state-of-the-art techniques to restore function and intimacy for men. He is also a national thought leader with over 85 peer-reviewed publications.

Meet Dr. John Sigalos

At Urology Austin, Dr. John Sigalos specializes in men’s health, including Peyronie’s disease, erectile dysfunction, and male infertility. Trained at UCLA’s top-ranked urology program, he combines surgical expertise with a compassionate, patient-first approach. Recognized for his work in Peyronie’s disease, Dr. Sigalos values long-term relationships with patients and is committed to improving their quality of life. He has authored over 20 urologic publications and is a member of multiple national medical associations.


If you’ve noticed changes in the shape of your penis or experienced discomfort during intimacy, you’re not alone. Many men face similar concerns, and Peyronie’s disease (PD) might be the underlying cause. This condition can feel overwhelming, but understanding what it is and the treatment options available can make all the difference in taking control of your health and well-being.

What is Peyronie’s Disease?

Peyronie’s disease is a treatable medical condition caused by scar tissue, known as plaque, forming under the skin of the penis. This plaque prevents the surrounding tissue from stretching normally, leading to a noticeable curvature or an indentation deformity during erections. This can cause discomfort, difficulty with sexual activity, and emotional distress.

Experts estimate that up to 13% of adult men may have PD, though the condition is often underreported. While its exact cause isn’t always clear, minor injuries to the penis during sexual activity or physical trauma are believed to play a role. There is also a genetic association to Dupuytren’s Contracture—a hand condition that causes curling of the 4th and 5th fingers.

It’s important to note that PD is not contagious or cancerous. It’s also most commonly seen in men over 40, with the likelihood increasing in older age groups.

Two Phases of Peyronie’s Disease  

Understanding how PD progresses can help in managing it effectively:

  • Active Phase (6-18 months): Plaque forms, and symptoms such as curvature, pain, and changes in the penis can worsen over time.
  • Stable Phase (after 18 months): Symptoms stabilize, and the curve or pain typically doesn’t get worse.

Symptoms to Watch For

The symptoms of PD can vary widely from person to person, but the most common ones include:

  • Curvature of the Penis: A clear bend during erections, which can range from mild to severe.
  • Plaque Formation: A firm lump or band of thickened tissue under the skin.
  • Penile Pain: Discomfort or pain, especially during erections, is common during the active phase.
  • Loss of Length or Girth: Changes in size due to the restricted stretching of the scarred tissue.

Additionally, PD can take a toll on emotional well-being. Many men report anxiety, frustration, and impacts on self-esteem. If you’re feeling this way, know that help is available, and you don’t have to manage these feelings alone.

Diagnosing Peyronie’s Disease

If you recognize these symptoms, seeing a urologist is the first step in your journey to recovery. Diagnosis may involve a physical exam, ultrasound imaging, and providing your doctor with photos of an erect penis to measure and analyze the curve. These steps might seem daunting, but they’re essential for creating an effective treatment plan.

Treatment Options for Peyronie’s Disease

The approach to treating PD depends on your symptoms, the progression of the disease, and how it’s affecting your quality of life. Here are the most common treatment paths:

Observation

For patients with mild symptoms that don’t interfere significantly with their daily life, doctors may recommend waiting to monitor the condition during its active phase.

Traction Therapy

Devices like RestoreX and Penimaster Pro help stretch and straighten the penis over time, especially when combined with other treatments like Xiaflex.

Your healthcare provider will work with you to decide which treatment is best based on your symptoms and lifestyle.

Intralesional Collagenase Clostridium Histolyticum (Xiaflex) in Combination with Modeling

The FDA-approved Collagenase Clostridium Histolyticum therapy involves injectable enzymes that break down scar tissue in the plaque, helping to reduce curvature. The treatment includes cycles of injections and requires additional steps such as gentle at-home penile modeling or traction therapy to improve results.

  • Best suited for men with a curvature of 30 degrees or more.
  • Requires oversight by trained professionals and adherence to at-home instructions for optimal outcomes.

Surgical Interventions

For more severe cases, surgery may be recommended after the disease has stabilized. Options include penile plication (straightening the penis), plaque removal with grafting, or penile prosthesis implantation (especially for those with accompanying erectile dysfunction).

Living Well with Peyronie’s Disease

Living with PD comes with its challenges, but many men find relief through the right combination of treatments and support. Here are some practices to consider for managing the condition and maintaining overall well-being:

  • Open Communication: Talk with your partner about how you’re feeling emotionally or physically. Clear communication can foster intimacy and reduce anxiety.
  • Seek Support: Join support groups or speak with a mental health professional if you’re experiencing emotional distress.
  • Follow Your Treatment Plan: Adhere to prescribed treatments, medications, or at-home exercises like penile modeling to achieve the best results.

Remember, Peyronie’s is manageable, and there are treatment options available to help you feel empowered and confident again.

What To Do If You Need Treatment

If you or someone you know is showing signs of PD, don’t wait to seek help—Urology Austin is here to help. Early diagnosis and treatment can significantly improve outcomes and quality of life.

Speak to a urologist or explore solutions, both non-surgical and surgical in order to take steps toward improving your quality of life. Your health and happiness are worth it.

Here’s what you can do right now:

  • Schedule a Consultation: Reach out to us to set up an appointment with one of our Men’s Sexual Health Program Providers. Call 512-788-9688 and make sure to mention that you’d like to see one of our experts in Peyronie’s disease and management.
  • Discuss Your Options: Our providers will walk you through your personalized care plan, answering any questions you might have along the way.
  • Explore Support: Be part of a compassionate, expert-driven community that prioritizes your care.

With locations throughout Central Texas, finding comprehensive, expert care has never been more convenient. Whether you’re newly diagnosed or looking for continued support in your treatment, Urology Austin is here for you.

Improve your quality of life today and take back your sexual health.

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